Anabolic steroids and testosteroneTestosterone Propionate is regarded as a fairly popular and injection sites for steroids anabolic steroid, as but to a anabolic steroids testosterone propionate lesser extent than most other esterified variants of Testosterone. This is because of the anabolic steroids testosterone propionate mentioned aspect of inconvenience concerning Testosterone Propionate doses and dosing schedules, which will be further explained in more detail. Testosterone in any of its forms serves as an absolutely essential anabolic steroid that should be utilized in literally every single cycle, and there are no exceptions propiomate this rule. Testosterone Propionate in particular is less commonly used as a first-time anabolic steroid by brand new beginners to the world tfstosterone anabolic sheroids. This is because of its short-acting nature with its short anabolic steroids testosterone propionate necessitating frequent Testosterone Propionate doses every other day injections at the very leastwhich presents a far greater degree of inconvenience for beginners, as the majority of newcomers might not enjoy such an inconvenient administration schedule.
Anabolic steroids and testosterone | Dopinglinkki
Although Testosterone itself may present side effects that other modified analogues and derivatives have avoided such as Estrogenic side effects, for example , Testosterone overall is considered the safest anabolic steroid if only for the reason that it is the anabolic hormone that the human body endogenously produces naturally. It then stands to reason that the human body is well accustomed to the effects of Testosterone on its cells and systems, and enough research has been conducted on Testosterone and its effects on the body that nearly all of the knowledge of Testosterone Propionate side effects possible are known to man, and this information is easily accessible.
There is in fact far more abundant solid scientific data in the form of clinical studies and information on Testosterone and its different ester types than any other anabolic steroid in existence. This is in contrast with other modified analogues of Testosterone. While as mentioned above, these modified analogues may avoid certain side effects that are inherently a part of Testosterone itself, they often may exhibit odd side effects and odd behavior unknown to science due to its modifications that essentially create an entirely new anabolic steroid.
This odd behavior would never be exhibited by Testosterone itself, being that Testosterone being the most natural anabolic steroid to the human body. With this having been established, Testosterone is not without its share of potential side effects. But it is our almost complete understanding of this compound that allows Testosterone Propionate side effects to be efficiently understood and dealt with. Testosterone itself possesses a moderate level of Estrogenic activity, whereby it holds a moderate affinity to bind to the aromatase enzyme the enzyme responsible for the conversion of Testosterone into Estrogen.
Therefore, a moderate level of aromatization is to be expected with Testosterone use. The result can be significant rises in Estrogen levels resulting from the conversion of Testosterone into Estrogen, especially when Testosterone Propionate it utilized at bodybuilding doses and doses required for performance and physique enhancement. Estrogenic Testosterone Propionate side effects should not be ignored for this reason, and the rate of aromatization usually always holds a direct correlation with the doses utilized.
It stands to reason that increasingly higher doses will usually be met with an increase in aromatization of Testosterone into Estrogen. Individuals should then understand that bodybuilding doses of Testosterone will often generate significant amounts of aromatization that must be dealt with in some way.
Individuals can elect to use an aromatase inhibitor, which serves to disable the aromatase enzyme so that Testosterone cannot be converted into Estrogen, effectively controlling Estrogen increases as the root cause. The other possible option is the use of a SERM Selective Estrogen Receptor Modulator such as Nolvadex, which instead acts to block Estrogen from attaching to receptor sites in breast tissue. SERMs such as Nolvadex will only serve to remedy the issue of gynecomastia caused by Estrogen, and will not actually reduce serum Estrogen levels in the body — an aromatase inhibitor is what is required for such an effect.
Estrogenic side effects include the following: Being that Testosterone is the prime male androgen, Testosterone Propionate side effects do include the aspect of androgenic side effects as well.
It also undergoes conversion into an even stronger androgenic metabolite, Dihydrotestosterone DHT. Testosterone possesses an androgenic strength rating of , which serves to exhibit a considerable amount of androgenic activity in the body.
However, Testosterone Propionate side effects in the area of androgenicity have more to do with the fact that Testosterone is converted into the aforementioned stronger and more potent androgen Dihydrotestosterone DHT via the 5-alpha reductase 5AR enzyme.
The 5-alpha reductase enzyme is present in large amounts in certain tissues, such as the scalp, prostate, and the skin. When Testosterone reaches these tissues, it undergoes a high rate of reduction into its more potent androgenic metabolite DHT.
It is DHT that is responsible for the greater severity of androgenic side effects. Ancillary drugs such as Proscar or Dutasteride can be utilized to effectively inhibit the 5-alpha reductase enzyme and thereby eliminate DHT at the root of its cause. This will not, however, completely eliminate androgenic side effects due to the fact that Testosterone itself possesses an androgenic strength rating of and will still act as an androgen in various tissues throughout the body even if the potential to convert into DHT is eliminated or reduced.
Androgenic side effects include: Testosterone Propionate side effects are no exception to this rule for each and every anabolic steroid in existence. Possible complete and permanent shut-down of these endocrine systems can result as well, especially resultant from excessively long cycle lengths. PCT protocols and programs are usually run for the duration of 4 — 6 weeks after all anabolic steroids have cleared from the body following the end of the cycle.
Hepatotoxic Side Effects Testosterone Propionate is not a Calpha alkylated anabolic steroid and therefore does not exhibit any measure of toxicity on the liver. The assurance of this fact rests in the studies that have investigated the potential for hepatotoxicity with Testosterone used at high doses mg daily, which equates to 2,mg weekly in several male test subjects for a 20 day period where the route of administration was actually oral instead of intramuscular injections. The result of the study was that no changes were observed .
It is also important to note that even if there were any measure of hepatotoxicity with Testosterone Propionate, its route of administration lies in injection, which avoids the aforementioned first pass through the liver something that only occurs with oral ingestion of a substance.
Therefore, hepatotoxicity is not of any concern where Testosterone Propionate side effects are concerned. Cardiovascular strain and negative cholesterol changes are all peripheral effects that fall under Testosterone Propionate side effects. It is one side effect that is exhibited by every single anabolic steroid in existence and is inherent to the nature of anabolic steroids, especially oral anabolic steroids. The result of such changes involves an increased risk of arteriosclerosis, and the degree to which these changes occur for the worse are usually dose-dependent with higher doses increasing the negative changes and the risks.
Other factors that affect these negative cholesterol changes are: The issue where hepatotoxicity is concerned mostly stems from certain anabolic steroids that possess the trait of exhibiting heavier resistance to hepatic metabolism than Testosterone is.
This is one of the main reasons as to why oral anabolic steroids exhibit varying levels of hepatotoxicity — the Calpha alkylation causes the anabolic steroid to become further resistant to being metabolized or broken down by the liver. Testosterone in particular has demonstrated in one clinical study to have only a mild impact on HDL cholesterol after a 12 week period where mg of Testosterone Enanthate was administered weekly.
From the data examined, it is very evident that the increase in Estrogen via aromatization and liver metabolism actually helps to offset the negative cholesterol changes from the use of supraphysiological amounts of anabolic steroids. This makes sense, considering Estrogen itself is known to promote positive impacts on cholesterol levels. Therefore, the use of an aromatase inhibitor and its impact on cholesterol profiles should always be remembered when any user is considering the addition of an aromatase inhibitor on cycle.
It is therefore advisable to instead use minimal doses of an aromatase inhibitor while on a cycle for the purpose of Estrogen control rather than total Estrogen level elimination.
The idea in such a case is to keep Estrogen levels within normal ranges and not allow them to skyrocket as a result of aromatization, but at the same time prevent them from dropping to near zero from the use of full doses of an aromatase inhibitor. Friedl K, Hannan C et al.
Metabolism 39 1 ;. Bhasin S, Woodhouse L. Am J Physiol Endocrinol Metab Dan's educational emphasis is on performance enhancement drugs PEDs , endocrinology, nutritional supplements and strategies for health, fat reduction, anti-ageing, muscle growth, disease control and vaccinations. Dan has had an interest in learning and writing about steroid use for over 15 years.